{"id":4567,"date":"2016-04-20T16:48:34","date_gmt":"2016-04-20T15:48:34","guid":{"rendered":"http:\/\/dev5.sclerodermie.ca\/?page_id=4567"},"modified":"2016-04-22T20:28:09","modified_gmt":"2016-04-22T19:28:09","slug":"pulmonary-arterial-hypertension","status":"publish","type":"page","link":"http:\/\/dev5.sclerodermie.ca\/en\/health-professionals\/abc-on-symptoms-and-treatments\/pulmonary-arterial-hypertension\/","title":{"rendered":"Pulmonary Arterial Hypertension"},"content":{"rendered":"

Symptoms and Treatments<\/h2>\n

Patients diagnosed with pulmonary arterial hypertension should be referred to a pulmonary hypertension center for experienced evaluation and management of this serious scleroderma complication.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u00a0<\/td>\n\n

Action<\/strong><\/span><\/p>\n<\/td>\n

\n

Most Common
Side Effects<\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<\/thead>\n

\u00a0<\/td>\n\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
\n

Endothelin Receptor Antagonists<\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

Ambrisentan (Volibris\u00ae)
<\/strong><\/p>\n<\/td>\n

Act on
blood vessels<\/td>\n		Peripheral edema, headache, decreased hemoglobin, nasal stuffiness, palpitations.<\/td>\n<\/tr>\n
\u00a0<\/td>\n<\/tr>\n
\n

Bosentan (Tracleer\u00ae)<\/p>\n<\/td>\n

Act on
blood vessels<\/td>\n		Headache, nasal stuffiness, flushing, liver function abnormality, flushing, pulmonary edema, low blood pressure.<\/td>\n<\/tr>\n
\u00a0<\/td>\n<\/tr>\n
\n

Macitan (Opsumit\u00ae)<\/p>\n<\/td>\n

Act on
blood vessels<\/td>\n		Nasal stuffiness, headache, anemia, bronchitis, sore throat, flu.<\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n
Prostaglandin Derivatives <\/strong><\/td>\n\u00a0<\/td>\n<\/tr>\n
\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
\n

Epoprostenol (Flolan\u00ae, Caripul\u00ae)<\/p>\n<\/td>\n

Act on blood vessels by inhibiting platelet aggregation<\/td>\nHeadache, dizziness, flushing, jaw pain, diarrhea, bone pain, potential serious infection associated with central line catheter in the chest wall.<\/td>\n<\/tr>\n
\u00a0<\/td>\n<\/tr>\n
Trepostinil (Remodulin\u00ae)<\/td>\nAct on
blood vessels\u00a0<\/td>\n		Pain at infusion site, headache, cough, diarrhea, nausea, flushing, jaw pain, skin rash, edema.<\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n
Calcium Channel Blockers
<\/strong><\/td>\n		\u00a0<\/td>\n<\/tr>\n
\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
Can be helpful
to a small
proportion of patients;
see Raynaud\u2019s section<\/a>.<\/td>\n		See
Raynaud’s section<\/a><\/td>\n		See
Raynaud’s section<\/a><\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n
Phosphodiesterase Type 5 (PDE5) Inhibitor<\/strong><\/td>\n<\/tr>\n
\u00a0<\/td>\n<\/tr>\n
Sildenafil citrate (Revatio\u00ae)<\/td>\nAct on blood vessels<\/td>\nHeadache, flushing, dyspepsia, flushing, nosebleeds, vision change, nasal stuffiness, diarrhea, insomnia.<\/td>\n<\/tr>\n
\u00a0<\/td>\n\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
Tadalafil
(Adcirca\u00ae)<\/td>\n		Act on blood vessels<\/td>\nHeadache, muscle pain, flushing, stomach upset, nausea, respiratory tract infection, nasal stuffiness.<\/td>\n<\/tr>\n
\n
\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Scleroderma Medications Guide (Canada)<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Symptoms and Treatments Patients diagnosed with pulmonary arterial hypertension should be referred to a pulmonary hypertension center for experienced evaluation and management of this serious scleroderma complication. \u00a0 Action Most CommonSide Effects \u00a0 \u00a0 \u00a0 Endothelin Receptor Antagonists Ambrisentan (Volibris\u00ae) Act onblood vessels Peripheral edema, headache, decreased hemoglobin, nasal stuffiness, palpitations. \u00a0 Bosentan (Tracleer\u00ae) Act […]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":357,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-professionnels.php","meta":[],"acf":[],"yoast_head":"\nPulmonary Arterial Hypertension - Sclerodermie<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/dev5.sclerodermie.ca\/en\/health-professionals\/abc-on-symptoms-and-treatments\/pulmonary-arterial-hypertension\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pulmonary Arterial Hypertension - 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